Respiratory Fluoroquinolones: Differences in the Details

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Newer fluoroquinolones and the management of respiratory tract infections.

Infections of the respiratory tract remain one of the leading causes of death in the United States [1]. The cost burden for bacterial infections of the upper and lower respiratory tract is tremendous; the cost alone of treating patients with communityacquired pneumonia (CAP) has recently been estimated to be close to $10 billion (US) [2]. In addition, the emergence of drugresistant pathogens pr...

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In vitro activity of fluoroquinolones against common respiratory pathogens.

The treatment of respiratory infections is often empiric, necessitating the use of agents with a broad range of antimicrobial activity. The fluoroquinolones, having activity against common respiratory pathogens, fit this description. New fluoroquinolones have been developed in an attempt to improve the in vitro activity against a wide variety of respiratory tract pathogens. The objective of the...

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Role of newer fluoroquinolones in lower respiratory tract infections.

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Treatment of respiratory tract infections with fluoroquinolones in Belgium

Belgian data on the treatment of respiratory tract infections with antibiotics in ambulatory care showed that fluoroquinolone use remains well controlled. Belgian guidelines have recommended moxifloxacin for CAP outpatients with comorbid conditions or outpatients in whom infection with atypical pathogens needs to be considered. Moxifloxacin is recommended in case of IgE-mediated ß-lactam allerg...

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Newer fluoroquinolones for treating respiratory infection: do they mask tuberculosis?

Possible masking of tuberculosis (TB) in treatment of community-acquired respiratory infection by newer fluoroquinolones has not been examined in randomised controlled trials. We undertook a randomised, open-label controlled trial involving adults with community-acquired pneumonia or infective exacerbation of bronchiectasis encountered in government chest clinics in Hong Kong. 427 participants ...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2004

ISSN: 1058-4838,1537-6591

DOI: 10.1086/383153